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Throughout the game, as well as killing zombies, rescuing survivors and trying to make it out of the Willamette Mall alive, Frank has to fight psychopaths: people who have gone insane due to the outbreak (Adam, Cliff, Sean, Paul, Larry, Steven) or are using it to their corrupted advantage (Jo, the Convicts, Marian) or just over-cautious people trying to survive (Cletus, the Hall family). Brock is not mainly a psychopath, he is just a soldier who is following his mission

Name Weapon Location Mission
Adam MacIntyre 2 Small Chainsaws Wonderland Plaza Out Of Control
Brock Mason Tank Construction site near Willamette Mall Overtime Mode
Cletus Samson Shotgun Huntin' Shack gun shop The Gun Shop
Cliff Hudson Machete Crislip's Home Saloon The Hatchet Man
Evan MacIntyre

Snow Cannon, Ice Grenades

Outside Fortune City Arena Snow Job
Harjit Singh 2 Impact Hammers Phenotrans laboratory Secure Lab
Jack Hall Sniper Rifle 2nd floor of Enterance Plaza Mark Of The Sniper
Jo Slade Stun Gun, Handgun Lovely Fashion House Above The Law
Kent Swanson Handgun Paradise Plaza Cut From The Same Cloth, Photo Challenge, Photographer's Pride
Larry Chiang Meat Cleaver Meat Processing Area The Butcher
Marian Mallon Phenotrans laboratory Secure Lab
Miguel Sanchez Baseball Bat Leisure Park The Prisoners
Paul Carson Molotov Cocktail Casual Gals Long Haired Punk
Reginald Jenkins Heavy Machine Gun Leisure Park The Prisoners
Roger Hall Sniper Rifle 2nd floor of Enterance Plaza Mark Of The Sniper
Sam Franklin Military Jeep Leisure Park The Prisoners
Sean Keanan Ceremonial Sword Colby's Movieland The Cult, A Strange Group
Steven Chapman Weapon Cart, Shotgun Seon's Food & Stuff Medicine Run
Thomas Hall Sniper Rifle 2nd floor of Enterance Plaza Mark Of The Sniper
True Eye Cult Hunting Knives, Dynamite Around the Mall after 'The Cult'

The Cult, A Strange Group